Patients who had previous lumbar spine surgery, recent lumbar spine trauma, those more than 50 years of age and those with poor quality radiographs were excluded.
There were 24 male and 17 female patients. The average age was 32.7 years. Of the 41 patients, 29 (70.7%) showed no significant instability. Six (15%) patients showed anterolisthesis, where flexion accentuated the forward displacement, while further six (15%) patients showed paradoxical motion. Statistical analyses found that patients with paradoxical motion had a significantly higher slip angle.
In this study, we have demonstrated that: (1) paradoxical motion in
spondylolytic spondylolisthesis is more common than previously thought. (2) Patients without anterolisthesis during flexion in dynamic radiographs may still have (paradoxical) instability. (3) Paradoxical motion may be more common in patients with a low sacral slope and increased learn more S63845 price lumbosacral lordosis.”
“Phthalates are developmental and reproductive toxicants for the fetus in pregnant rodents, and the ability of phthalates to penetrate the placenta have been reported.
The aims of this study were to evaluate the association between maternal urine excretion, the exposure of fetus to phthalates in amniotic fluid, and the health of newborns. Amniotic fluid and urine samples from pregnant women were collected to measure five phthalate monoesters using liquid chromatography/tandem mass spectrometry (LC/MS-MS) selleck and the newborns birth weight. gestational age, and anogenital distance (AGD) were collected. The median levels of three phthalate monoesters in urine and amniotic fluid were 78.4 and 85.2 ng/mL monobutyl phthalate (MBP); 24.9 and 22.8 ng/mL
mono-(2-ethylhexyl) phthalate (MEHP): 19.8 and Not Detected monoethyl phthalate (MEP). We found a significant positive correlation only between creatinine adjusted urinary MBP and amniotic fluid MBP (R(2) =0.156, p < 0.05) in all infants and, only in female infants, a significantly negative correlation between amniotic fluid MBP, AGD (R=-0.31, p < 0.06), and the anogenital index adjusted by birth weight (AGI-W) (R=-0.32, p < 0.05). Although the influence of prenatal di-n-butyl phthalate (DBP) exposure on the endocrinology and physiology of the fetus is still a puzzle, our data clearly show that in utero exposure to phthalates in general has anti-androgenic effects on the fetus. (C) 2008 Elsevier Ltd. All rights reserved.”
“Background: Evaluate and compare the utility of serum folate receptor alpha (FRA) and megakaryocyte potentiating factor (MPF) determinations relative to serum CA125, mesothelin (MSLN) and HE4 for the diagnosis of epithelial ovarian cancer (EOC).
Methods: Electrochemiluminescent assays were developed for FRA, MSLN and MPF and used to assess the levels of these biomarkers in 258 serum samples from ovarian cancer patients.