4%) of them received a pre-emptive transplantation. For the nonpre-emptive patients, mean Protein Tyrosine Kinase inhibitor time on pretransplant dialysis was 3.4 +/- 3.2 years. Pretransplant factors independently related to pre-emptive transplantation were year of transplantation, centre and recipients characteristics: gender, diabetes history, blood group and donor age. Patients with pretransplant dialysis were three times more likely to have delayed graft function than pre-emptive transplant patients, and were 10 times more likely to receive post-transplant dialysis. Five-year patient survival was 92.9%. Five-year graft survival was 89.0%. Neither pre-emptive transplantation nor
time on dialysis was significantly associated with patient and/or graft survival.”
“Background: Due to demographic change, the advanced elderly represent the fastest growing population group in Europe. Health problems tend to be frequent and increasing with age within this cohort.
Aims of the study: To describe and compare health status of the elderly population in
six European countries and to analyze the impact of socio-demographic variables on health.
Methods: In the European Study of the Epidemiology of Mental Disorders (ESEMeD), representative non-institutionalized population samples completed the EQ-5D MCC950 clinical trial and Short Form-12 (SF-12) questionnaires as part of personal computer-based home interviews in 2001-2003. This study is based on a subsample of 1659 respondents aged >= 75 years from Belgium (n = 194), France (n = 168), Germany (n = 244), Italy (n = 317), the Netherlands (n = 164) and
Spain (n = 572). Descriptive statistics, bivariate-(chi-square tests) and multivariate methods (linear regressions) were used to examine differences in population health.
Results: 68.8% of respondents reported problems in one or more EQ-5D dimensions, most frequently pain/discomfort (55.2%), followed by mobility (50.0%), usual activities (36.6%), self-care (18.1%) and anxiety/depression (11.6%). The proportion of respondents reporting Kinesin inhibitor any problems increased significantly with age in bivariate analyses (age 75-79: 65.4%; age 80-84: 69.2%; age >= 85: 81.1%) and differed between countries, ranging from 58.7% in the Netherlands to 72.3% in Italy. The mean EQ VAS score was 61.9, decreasing with age (age 75-79: 64.1; age 80-84: 59.8; age >= 85: 56.7) and ranging from 60.0 in Italy to 72.9 in the Netherlands. SF-12 derived Physical Component Summary (PCS) and Mental Component Summary (MCS) scores varied little by age and country. Age and low educational level were associated with lower EQ VAS and PCS scores. After controlling for socio-demographic variables and reported EQ-5D health states, mean EQ VAS scores were significantly higher in the Netherlands and Belgium, and lower in Germany than the grand mean.
Conclusions: More than two thirds of the advanced elderly report impairment of health status. Impairment increases rapidly with age but differs considerably between countries.