5 g). Although the total fibre content was higher (21.9 g) in the control diet, the quantity in the soluble part was lower (3.9 g).The difference in available carbohydrate (avCHO = total check details carbohydrate minus fiber) is the better explanation: control chow has 45.5 cho-21.9 fiber = 23.6 g avCHO while the oat bran diet contains 45.6 cho-18.9 fiber = 26.7 g avCHO. It is a 13% increase in the oat bran chow. CB-839 changes in the intestinal microflora that occur with the consumption of prebiotic fibres may potentially

mediate immune changes via: the direct contact of lactic acid bacteria or bacterial products (cell wall or cytoplasmic components) with immune cells in the intestine; the production of short-chain fatty acids from fibre fermentation; or by changes in mucin production. The link between oat bran and immune system its regard with the content of β-glucan, especially water-soluble β-glucan. This soluble fiber can enhance the activities of both

the innate and specific immune system components via direct activation of specific receptors on macrophage, neutrophils, and NK cells [30, 31] or indirectly after activation of pinocytic M-cells located in the Peyer’s patches of the small intestine [32, 33]. There is increasing evidence that fermentable dietary click here fibres and the newly described prebiotics can modulate various properties of the immune system, including those of the gut-associated lymphoid tissues (GALT). In published data on the immune system of the same experimental group, Donatto [34] demonstrated that the EX-O group presented better phagocytic capacity of peritoneal macrophages, increased amount of lymphocytes from lymph nodes and shows less leukocytosis very after

exhausting exercise. We found no side effects in this study, including no increase in the plasma concentration of pro inflammatory cytokine. β-glucan found in oat bran could not exaggerate the inflammatory response to severe exercise. Glycogen metabolism is largely controlled by the actions of glycogen synthase and glycogen phosphorylase enzymes [35]. The gene expression of Glycogen synthase increased after both resistance and aerobic training, but not when aerobic exercise was combined with a high CHO diet in comparison with diet without exercise [36]. In the present study, we found a lower expression of the glycogen synthetase enzyme in the soleus muscle in the EXO group. Probably, the higher glycogen levels in the soleus muscle had an important relationship with the impaired glycogen synthetase expression. It may reflect a lower need for re-synthesis [37] since this group presented higher glycogen concentrations in the soleus when compared with exhaustion of the non-oat bran enriched diet group (EX). The oat bran is a nutritional search of dietary fiber, especially soluble fiber and this nutriente may retard the absorption of nutrients by the intestinal villosities [38].