7%) and 38 were female (25.3%). The mean age of the group was 44.3 ± 8.3 years, and the median age was 44 years. The

mean age of the male patients was 44.8 ± 8.2 years and that of the female patients was 43 ± 8.8 years; this difference was not significant. Of the 150 patients, selleck 19 (17.0%) of the male patients and five (13.2%) of the female patients were >50 years old. Men were more often single than of other marital status, and women were more often married or widowed (P<0.001). The most common type of cohabitation was living with partner or children, or both (48.7%); cohabitation was significantly more frequent in women than in men (65.8%vs. 42.9%, respectively; P=0.015). A summary of the sociodemographic, epidemiological and clinical data is presented in Table 1. The mean PHS value was 52.3 ± 8.8 and the mean MHS value was 49.3 ± 9.9. The distribution of mean values for the MOS-HIV questionnaire is shown in Table 2. We found that women had lower scores than men in Pain (P=0.038) and Cognitive Functioning (P=0.037), with no differences in the other HRQL domains. Patients >50 years old had higher scores than the youngest age category in Pain patients without children got higher scores than patients with children in Smad inhibitor (P=0.018), Health Distress (P=0.018) and Cognitive

Functioning (P=0.004). Single patients (P=0.020), those who lived alone (P=0.006) and those without children (P<0.001) had higher scores for General Forskolin clinical trial Health Perceptions. In this last group, patients without children got higher scores than patients with children in Energy (P=0.018), Quality of Life (P=0.007), PHS (P=0.005) and MHS (P=0.012) scores were higher in patients with children. We found no significant differences for educational background or income level. Former smokers had higher scores than other patients in the Health Distress domain (P=0.032). Patients with a history of injecting drug use (IDU) had lower

scores than other patients in General Health Perceptions (P=0.059), Pain (P=0.005), Physical Functioning (P=0.003), Social Functioning (P=0.070) and PHS (P<0.001). Patients who stated that they were homosexual had lower scores than other patients in General Health Perceptions (P=0.007), Pain (P=0.034), Physical Functioning (P=0.002) and MHS (P<0.001). Furthermore, patients who contracted HIV infection through sharing of needles among heterosexual injecting drug users had lower scores than other patients in General Health Perceptions (P=0.034). In terms of immune system status, we did not find a relationship between the domains of the MOS-HIV questionnaire and the variables CD4 cell count and viral load. However, patients with CDC category stage C disease (European classification) had higher scores than other patients in Mental Health (P=0.023), Energy (P=0.050), Cognitive Functioning (P=0.046), Quality of Life (P=0.018) and MHS (P=0.025).