Today, many aspects of hormone role in regulating oxidant – antioxidant balance still remain obscure. Physical and psychological stressor, which activate pituitary-adrenal axis, cause oxidative damage (Mancini et al., 2010).Oxidative stress and inflammation are traditionally associated with fatigue and impaired recovery from exercise and antioxidant could play a positive role to reduced inflammation markers and cortisol response (Tidus et al.,

1995). Furthermore a relationship between sex hormones Sotrastaurin cell line and plasmatic Total Antioxidant Capacity (TAC) was observed. TAC is significantly correlated with total testosterone in male subjects (Mancini et al., 2010). Aim of this work is to obtain first data which correlate plasmatic oxidative stress (TAC and lipid peroxidation) with levels of testosterone and cortisol (T/C),recommended as good markers of training stress (Banfi et al., 1993), during season of a top team of the

Italian Soccer League. Furthermore during the same season we assessed Napabucasin the same levels of testosterone and cortisol in saliva and correlated them with obtained data in plasma. To evaluate oxidative stress in plasma we used two validated techniques OXY-Adsorbent and d-ROMs test. The first one measures plasma TAC against a massive oxidative insult induced in vitro by a hypochlorous acid solution while d-ROMs test measures lipid peroxides amount produced by ferrous iron solution action.Our data indicate that there is no correlation between TAC and d-ROMs showing why them as the best marker for oxidative stress.

There is a correlation between T/C GW-572016 molecular weight databoth in plasma and saliva with d-ROMs. T/C Ratio decrease from July to January and remainsroughlystable, with aminimumincreasein April both in plasma and saliva. It’s an important result that validate the possibility to assess hormone levels in both physiological fluids and confirm that saliva can be used as an alternative non invasive method to evaluate hormonal levels.”
“Background Gastric intestinal, skeletal muscle and neurological symptoms are just some of the possible effects of alimentary intolerances that may represent a risk for one’s health and may frustrate the athlete’s practice benefits and thwart the performance. The immunological tolerance recovery and the re-establishment of a normal diet are generally reached by means of strict dietetic schemes (a turnover or elimination diet) requiring a strong effort into changing one’s diet habit. In the elite soccer athlete, an intense competitive schedule including long transfers represents another risk to these dietetic therapies fulfilment that may even worsen the symptomatology once the allergens responsible for the intolerances are again within the diet.