(c) 2007 Elsevier Ireland Ltd. All rights reserved.”
“Aims: Acid and heat tolerance of 17 persistent and 23 nonpersistent Listeria monocytogenes strains, recovered from three meat-processing plants, were investigated.
Methods and Results: The isolates were genotyped by pulsed-field gel electrophoresis and categorized into persistent strains according to the frequency of the strain and duration of the contamination. The persistent and nonpersistent strains
were challenged to acidic conditions (pH 2.4 for 2 h, 1 mol l(-1) HCl were used to acidify the suspension) and to heat (55 degrees C for 40 min) to receive a reduction in cell count. Listeria monocytogenes strains showed large variation in acid tolerance (over 6 log units) Histone Methyltransferase inhibitor and in heat tolerance (3 log units). The persistent strains showed higher tolerance to acidic conditions than the nonpersistent strains (Student’s t-test, P = 0.02), but significant differences in heat tolerance between persistent and nonpersistent strains were not observed.
Conclusions: The results indicate that acid tolerance may have an effect on the persistence of L. monocytogenes contamination.
Significance and Impact of the Study: This study highlights the fact that there are great differences in acid and heat tolerances between L. monocytogenes strains, and the preventive measures should be designed to be effective against the most
“It was discovered fifty years ago that a minced skeletal muscle replaced in its bed is able to regenerate. This regeneration is due to the presence of quiescent muscle precursor cells so-called satellite EPZ5676 solubility dmso cells in the adult muscle which proliferate and fuse to regenerate new centronucleated fibres when the muscle is damaged. These observations open therapeutic perspectives
and, in this study, we attempted to test in the mouse whether fragments of minced muscle regenerate new fibres to fill the gap resulting from the trans-section and retraction of the extensor digitorum longus muscle (EDL). When untreated this gap never regenerates. In agreement with Studitsky, we observed that a minced EDL replaced in its bed regenerates fibres that are spatially disorganised. Minced fragments of abdominus rectus muscle placed in the gap resulting of the trans-section of the EDL regenerate muscle fibres in the gap with a Chorioepithelioma better organisation that in the whole minced muscle. These results could have putative clinical applications, for instance in the prevention of incontinence following prostatectomy which implies removal excision of a large part of the striated urethral sphincter. (c) 2007 Elsevier Ireland Ltd. All rights reserved.”
“Children with Developmental Coordination Disorder (DCD) are reported to have high temporal variability in tasks requiring precise timing. The current study examined whether this timing deficit was due to the cerebellar ‘explicit timing’ process in the discontinuous, but not the continuous movement.