CONCLUSIONS: A combination of physician billing and hospital discharge abstracts can be used to identify patients with IHD. Population prevalence of IHD can be measured using administrative data.”
“Objective. The purpose of this study was to compare the sealing ability of the temporary restorative materials Cavit-G, Ketac Molar Easymix, and IRM with a new light-curing temporary material, Clip, using a methylene blue dye penetration test.
Study design. Endodontic access preparations were prepared in 48 intact extracted human premolars. The teeth were divided into 6 groups, including positive and negative control groups.
After access preparation, cotton pellets were placed in the pulp chamber so that the space remaining for the restoration was 4 mm. After thermal cycling for 500 cycles (5 degrees
C-55 degrees C), the teeth were immersed in 2% methylene blue solution at neutral (pH = 7.0) in an incubator for leakage assessment. The teeth were SNX-5422 price sectioned, and the greatest depth of dye penetration was recorded. Marginal leakage was evaluated with a stereomicroscope.
Results. Positive control sections exhibited complete dye penetration, and negative controls had none. In the experimental groups, the differences in the leakage scores of the Clip and Cavit-G groups and the other 2 groups were very marked. There were no statistically significant difference in marginal leakage between Cavit-G and Clip.
Conclusion. The new light-curing temporary material Clip seals against marginal leakage as effectively as Cavit when used as a temporary filling. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod PARP inhibitor 2009; 108: e67-e70)”
“Sickle-cell disease (SCD) is a wide-spread inherited hemolytic anemia that is due to a point mutation, leading to the substitution of valine for glutamic acid, causing a spectrum of clinical manifestations in addition to hemolysis and anemia. Acute painful crisis is a common sequela that can cause significant morbidity and negatively impact the patient’s quality of life. Remarkable
improvements in the understanding of the pathogenesis of this clinical syndrome and the role of cell adhesion, inflammation, and coagulation in acute painful crisis have led to changes in the management of pain. Due to the endemic nature of SCD in various parts of the Middle East, a group of physicians and scientists from the United States and Middle East recently met to draw up a LY2835219 in vitro set of suggested guidelines for the management of acute painful crisis that are reflective of local and international experience. This review brings together a detailed etiology, the pathophysiology, and clinical presentation of SCD, including the differential diagnoses of pain associated with the disease, with evidence-based recommendations for pain management and the potential impact of low-molecular-weight heparin (LMWH), from the perspective of physicians and scientists with long-term experience in the management of a large number of patients with SCD.”